Cisplatin and hypokalemia
WebJun 2, 2024 · Background: Cisplatin-associated acute kidney injury (C-AKI) is common. Predictive factors of C-AKI include age > 60 years, hypertension, cisplatin dose, diabetes, and serum albumin < 3.5g/L. The association between C-AKI and hypokalemia, hypomagnesemia or hyponatremia has not been well characterized to date. WebApr 15, 2024 · Eventually, nephrotoxicity complicated by hypomagnesaemia was confirmed, and cisplatin-induced nephrotoxicity led to the final diagnosis of a familial form of …
Cisplatin and hypokalemia
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WebHypokalemia may develop with furosemide, especially with brisk diuresis, inadequate oral electrolyte intake, when cirrhosis is present, or during concomitant use of corticosteroids, ACTH, licorice in large amounts, or prolonged use of laxatives. ... There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly. In ... WebMar 25, 2024 · The most common laboratory findings include: hyponatremia, hyperkalemia, and anemia [ 4 ]. Hydrocortisone is the mainstay of treatment, and fludrocortisone is added to replace mineralocorticoid deficiency. Usually, hydrocortisone doses are divided into two or three doses, with the highest dose in the morning to mimic the circadian rhythm.
WebHypomagnesemia generally resolves with cessation of therapy. Cisplatin can cause increased magnesium losses by the kidneys as well as generalized decrease in kidney function. Magnesium loses can be severe and persist despite discontinuation of cisplatin. WebAug 1, 2004 · Nephrotoxicity after cisplatin administration usually manifests as increased serum creatinine and blood urea nitrogen (BUN) levels, as well as electrolyte …
Web21 hours ago · The EARLY-MYO-BC trial is the first to explore the cardiac impacts of pyrotinib in the neoadjuvant setting for this patient population. Patients are currently … WebJun 2, 2024 · Background: Cisplatin-associated acute kidney injury (C-AKI) is common. Predictive factors of C-AKI include age > 60 years, hypertension, cisplatin dose, …
WebFirst-line multiagent chemotherapy comprises doxorubicin, cisplatin, and high-dose methotrexate (MAP regimen) . ... Regarding toxicity, rash and hypokalemia was the most common grade 3 adverse event, and one death from end organ failure was reported that was possibly related to the drug.
http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf darlings andy griffith showWebDigitalis therapy may exaggerate metabolic effects of hypokalemia, especially myocardial effects. All patients receiving LASIX therapy should be observed for these signs or symptoms of fluid or ... There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as ... darlings associatesdarlings are coming andy griffithhttp://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf darlings and the franksWebNational Center for Biotechnology Information bismarck public school staffWebCisplatin-based combination chemotherapy is recommended as first-line systemic therapy for patients with metastatic BC based on a relative risk of nearly 50%. 44 The … darlings augusta maine largest dealershipWebApr 10, 2024 · Med-Surg Nursing. Hypocalcemia is when there are low levels of calcium in the blood. Calcium is an electrolyte that plays a vital role in many bodily functions, including muscle contraction, nerve transmission, and bone formation. Various factors, including nutritional deficiencies, medications, and underlying medical conditions, can all lead ... bismarck public schools solheim