WebProvided is an siRNA conjugate targeting FAP-positive cells, comprising: a ligand portion targeting FAP, an siRNA portion that inhibits expression of survival genes in FAP-positive cells, and a linker portion located between the ligand portion and siRNA portion. Also provided are a method for preparing the siRNA conjugate, and a pharmaceutical … Web23 apr. 2024 · Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive disease harboring significant morbidity and mortality despite recent advances in therapy. …
Idiopathic Pulmonary Fibrosis Causes and Risk Factors
Web14 sep. 2010 · Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease (ILD) affecting the pulmonary interstitium. Other forms of interstitial lung disease exist, and in some cases, an environmental etiology can be delineated. The diagnosis of IPF is typically established by high-resolution CT scan. Web12 apr. 2024 · If there is a clinical suspicion of an autoimmune condition, consultation with a rheumatologist—possibly in a multidisciplinary discussion - and more extensive serologic testing are recommended, including ANCA, rheumatoid factor, anti-ENA screen, that determines the levels of seven different autoantibodies including anti-Sm, anti-RNP, anti … danish raisin holland
Trauma-Related Disorders: Types and Treatment Options
WebRheumatoid factor (RF) is the autoantibody that was first found in rheumatoid arthritis.It is defined as an antibody against the Fc portion of IgG and different RFs can recognize … Web11 okt. 2024 · It should be noted that CTD could be the cause of interstitial lung disease (ILD) in the first place, and lung transplantation is often offered to patients with a variety of CTDs, including rheumatoid arthritis, systemic sclerosis, systemic lupus erythematosus, and … Web1 dec. 2024 · In other words (I think) IF Rheumatoid Factor shows up in a blood test it can mean there is inflammation in some other area of the body and not just the joints and … birthday certificate office