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Lamp2蛋白作用

TīmeklisLamp-2：溶酶体膜蛋白，可用于监测自噬体与溶酶体融合。 LysoTrackerTM 探针：有红或蓝色可选，显示所有酸性液泡。 pDsRed2-mito：载体，转染后表达一个融合蛋白（红色荧光蛋白+线粒体基质定位信号），可用来检测线粒体被自噬掉的程度（Mitophagy）。 MitoTraker探针：特异性显示活的线粒体，荧光在经过固定后还能保留。 Hsp60：定 … TīmeklisProduct Specific Information. PA1-655 detects lysosome-associated membrane protein-2 (LAMP2) from rat, mouse and human tissues. PA1-655 has been successfully used in Western blot, immunofluorescence, and immunohistochemistry. By Western blot, this antibody detects glycosylated and non-glycosylated LAMP-2, depending on the lysis …

LAMP2 - an overview ScienceDirect Topics

Tīmeklis2024. gada 21. marts · LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and Left … Tīmeklis2016. gada 14. sept. · LAMP2 accumulated perinuclearly as well as at the edge and at the extensions of NE cells. Since LAMP2 is a membrane protein present in lysosomes, we used lysotracker, an acid-dependent dye, to determine co-localization of LAMP2 and these acidic subcellular compartments . Lysotracker staining quantification … tooling for honeycomb structure in aircraft https://aurinkoaodottamassa.com

LAMP2: a major update of the database linking antimicrobial …

Tīmeklis2024. gada 8. dec. · Also known as Summary The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. http://www.bioon.com.cn/doc/showarticle.asp?newsid=74708 Tīmeklis2024. gada 24. nov. · Lamp2b-HuR融合蛋白功能化的外泌体能够将被RNA结合基序识别的RNA靶标驱动至溶酶体以在受体细胞中降解。 该系统在富含溶酶体的巨噬细胞中 … tooling foam block

Lysosome-associated membrane protein-2 deficiency increases ... - PubMed

Category:LAMP2: a major update of the database linking antimicrobial …

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Lamp2蛋白作用

Bioss Anti-LAMP2/FITC 大秀 Nature Nanotechnology: 肿瘤免疫治 …

Tīmeklis2024. gada 15. okt. · LAMP2 is thought to protect the lysosomal membrane from proteolytic enzymes within lysosomes and to act as a receptor for proteins to be imported into lysosomes (Fukuda, 1994).Kain et al. (2008) found that virtually all individuals with pauci-immune focal necrotizing glomerulonephritis (FNGN) had … Tīmeklis2024. gada 24. nov. · Lamp2b-HuR融合蛋白功能化的外泌体能够将被RNA结合基序识别的RNA靶标驱动至溶酶体以在受体细胞中降解。 该系统在富含溶酶体的巨噬细胞中特别有效，并作为RNA抑制的替代策略。 工程化外泌体的模式图 作为原理验证研究，RNA结合蛋白HuR与Lamp2b的C末端融合，Lamp2b是一种位于外泌体和溶酶体中的膜蛋白 …

Lamp2蛋白作用

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Tīmeklis上期小优跟大家介绍了一部分特别常用的细胞器marker [细胞器常用蛋白marker全攻略（上）]，这次咱们再来看看剩下的一些常用的和一些特殊结构的蛋白marker，包括 …

Tīmeklis大量证据表明自噬通路在多种疾病与生理过程中起着重要作用，如：神经系统疾病、肿瘤、心血管疾病、感染、代谢性疾病、自身免疫性疾病等等，自噬通路也就成为是很多疾病潜在的靶向治疗通路。. 大隅良典因“ … TīmeklisLAMP2 has been suggested to play a role in protection of the lysosomal membrane from autodigestion, to maintain the acidic environment of the lysosome and to serve as an …

Tīmeklis2024. gada 25. aug. · LAMP2, an updated version of LAMP, holds 23 253 unique AMP sequences and expands to link 16 public AMP databases. In the current version, … Tīmeklis2024. gada 8. febr. · LAMP2 gene encodes for three proteins, LAMP2A, LAMP2B, and LAMP2C, through an event of alternative splicing involving the exon 9 (in human) 5. The three isoforms share an identical luminal portion ...

Tīmeklis2024. gada 31. aug. · The protein encoded by the LAMP2 gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with …

Tīmeklis2024. gada 7. nov. · Lamp2 knockout (KO) mice are characterized by disrupted autophagy and phagocytosis in hepatocytes, neurons, and leukocytes (23–26). Loss-of-function mutations of the human LAMP2 gene cause Danon disease, a lysosomal storage disorder characterized by cardiomyopathy, skeletal myopathy, and mental … physics-basedTīmeklisRab7 和 Rab9 是小 Rab GTP 酶 Ras 超家族的成员 (1)。. 两种蛋白都位于晚期内体，但能发挥不同的功能。. Rab7 结合 RIPL效应蛋白可调控从早期内体到晚期内体再到溶 … physics-based animation pdfTīmeklis2024. gada 21. marts · LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and Left Ventricular Noncompaction . Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System . tooling for compositesTīmeklis2015. gada 10. dec. · The protein LAMP2 functions to protect lysosomal membranes from acid proteolysis. In this study, the authors show that malignant cells adapt to the acidic tumour microenvironment by redirecting ... physics based animation pdfTīmeklisCells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on autophagosomes, which is the most likely explanation for the lack of fusion between autophagosomes and lysosomes (PubMed:27628032). Required for normal degradation of the contents of autophagosomes (PubMed:27628032). tooling gelcoat for mold makingTīmeklisA. The quantification of the colocalization between a lysosomal protein such as LAMP2 and LC3 could be used via a standard immunofluorescence protocol (fixation using 4% PFA (10 min) and permeabilization using 0.1% Triton X-100 (5 min)) as an alternative method to monitor autophagic flux. The primary antibodies used for this alternative … physics based data modelsTīmeklis使用人 lamp2 蛋白氨基端特异的重组蛋白对动物进行免疫接种来产生单克隆抗体。 背景 溶酶体相关膜蛋白 1 和 2（LAMP1 和 LAMP2）是两种含量丰富的溶酶体膜蛋白 … physics based character controller unity